In late November 2025, EPA posted a webpage entitled “Pesticides Containing a Single Fluorinated Carbon” stating that pesticides containing a single fluorinated compound do not contain PFAS. Specifically, regarding pesticides registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA’s webpage states that “EPA-approved single fluorinated compounds are not forever chemicals, they are not PFAS, and do not pose any risks of concern when used as labeled.”

In support of this position, EPA’s webpage states that, “[i]n 2023, EPA’s Office of Pollution Prevention and Toxics (OPPT) established a definition for PFAS that specifically does not include single fluorinated carbons.” The referenced definition appears to be the structural definition of PFAS adopted in EPA’s 2023 rule establishing one-time PFAS reporting pursuant to the Toxic Substances Control Act (TSCA) section 8(a)(7):

PFAS is defined as including at least one of these three structures:

• R-(CF₂)-CF(R′)R″, where both the CF₂ and CF moieties are saturated carbons;

• R-CF₂ OCF₂ -R′, where R and R′ can either be F, O, or saturated carbons; and

• CF₃ C(CF₃)R′R″, where R′ and R″ can either be F or saturated carbons.

EPA’s webpage further states that “[e]xtensive scientific evidence and public input demonstrate molecules with only one fluorinated carbon generally lack the persistence and bioaccumulation properties that are commonly associated with forever chemicals” and that “[s]ingle fluorinated pesticides registered or proposed for use by EPA have been registered in other countries, including the European Union, Canada, and Australia, among others.”

EPA’s webpage on pesticides containing a single fluorinated carbon can be found here, and EPA’s 2023 rule establishing one-time PFAS reporting pursuant to TSCA section 8(a)(7) can be found here.